Which lab studies are performed in the workup of submandibular sialadenitis/sialadenosis?

Updated: May 12, 2020
  • Author: Adi Yoskovitch, MD, MSc; Chief Editor: Arlen D Meyers, MD, MBA  more...
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See the list below:

  • In evaluating the patient with sialadenitis, steps should be taken in the following order: history, physical examination, culture, laboratory investigation, radiography, and if indicated, fine-needle aspiration biopsy (see History and Physical).

  • Laboratory investigations should begin with culture of the offending gland (if possible, prior to the administration of antibiotics).

  • Blood cultures should be obtained in the patient exhibiting bacteremia or sepsis.

  • As a rule, needle aspiration of a suspected abscess is not indicated.

  • Routine electrolytes and complete blood cell count with differential should be obtained to assess for any evidence of dehydration or systemic infection.

  • If a diagnosis of autoimmunity is entertained, serum analysis for antinuclear antibody, SS-A, SS-B, and erythrocyte sedimentation rate should be conducted.

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