What is the role of CHARGE syndrome in the etiology of congenital facial paralysis?

Updated: Jan 07, 2019
  • Author: Alan D Bruns, MD, FACS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

This acronym stands for colobomata, heart disease, atresia of choanae, retarded growth, genital hypoplasia, and ear anomalies. Multiple cranial nerves may be involved in this condition. At least 1 cranial nerve is involved in 75% of cases, and 2 or more cranial nerves are involved in 58% of cases. Of patients who have cranial nerve involvement, 60% involve cranial nerve VIII, 43% involve cranial nerve VII, and 30% involve cranial nerves IX and X. [23, 24]


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