What is the role of medications in the treatment of sleep-disordered breathing (SDB)?

Updated: Feb 13, 2020
  • Author: Vittorio Rinaldi, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Other drugs that have been investigated for treatment of sleep apnea include progestational agents, aminophylline, acetazolamide, L-tryptophan, naloxone, baclofen, bromocriptine, chlorimipramine, and prochlorperazine. For the most part, these have not shown a consistently helpful effect on SDB. However, a study of the use of acetazolamide in patients with OSA and comorbid hypertension found that this agent reduced blood pressure, vascular stiffness, and SDB in this setting. [93]


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