Which histologic findings are characteristic of sleep-disordered breathing (SDB)?

Updated: Feb 13, 2020
  • Author: Vittorio Rinaldi, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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The histology of the soft palate and uvula in snorers and patients with OSAS has been investigated by many authors. [58, 59]  Some authors observed muscular atrophy, dilatation and congestion of the blood vessels, lymphocytic infiltrations, and hypertrophy of superficial salivary glands localized between the muscle bundles and epithelium. Those histopathologic changes were related to the influence of the vibration on the soft palate and uvula and were considered responsible for the excessive flaccidity of these structures.

Other authors found contents of glands, muscle, fat, blood vessels, and the epithelium in the uvula and the soft palate to be similar in OSAS patients and control subjects.

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