What are the characteristics of major aphthous ulcers (MjAUs)?

Updated: May 11, 2020
  • Author: Jaisri R Thoppay, DDS, MBA, MS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Characteristics of MjAUs (ie, Sutton ulcers, periadenitis mucosa necrotica recurrens [PMNR]) include the following:

  • They are larger, of longer duration, of more frequent recurrence, and often more painful than MiAUs.

  • They are round or ovoid like MiAUs but are larger and associated with surrounding edema.

  • They reach a large size, usually about 1 cm in diameter or even larger.

  • They are found on any area of the oral mucosa, including the keratinized dorsum of the tongue or palate.

  • They occur in groups of only a few ulcers (ie, 1-6) at one time.

  • They heal slowly over 10-40 days.

  • They recur extremely frequently.

  • They may heal with scarring.

  • They occasionally are found with a raised erythrocyte sedimentation rate or plasma viscosity.

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