Which histologic findings are characteristic of cricoarytenoid (CA) joint fixation?

Updated: Jul 27, 2021
  • Author: Paul C Bryson, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Histologic involvement of the cricoarytenoid (CA) joint was found in 47-78% of patients with rheumatoid arthritis examined on postmortem studies.

Early changes include thickened synovium and cellular hyperplasia with a plasma cell and/or lymphocytic infiltrate. Late changes include effusions originating from the hypertrophied lining leave fibrin deposits within the joint cavity. Progressive alterations lead to destruction of the articular surfaces. The ultimate loss of joint space is secondary to a reparative process laying down vascular, fibrous, and fatty tissue.


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