What is the role of taste and smell disorders in Down syndrome?

Updated: Dec 11, 2018
  • Author: Eric H Holbrook, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Answer

A study by Cecchini et al found severe olfactory impairment in persons with Down syndrome, with these individuals performing worse than euploid controls on tests of odor detection threshold, odor discrimination, and odor identification. Among 56 subjects with Down syndrome, 27 demonstrated functional anosmia. [27]


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