Which antibiotics are used in the treatment of acute otitis media (AOM)?

Updated: Sep 25, 2019
  • Author: John D Donaldson, MD, FRCSC, FACS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Antibiotics are the only medications with demonstrated efficacy in the management of AOM; therefore, these agents are the initial therapy of choice. The antibiotic chosen should cover most of the common bacterial pathogens and be individualized for the child with regard to allergy, tolerance, previous exposure to antibiotics, cost, and community resistance levels. Duration of treatment may also be a consideration in the choice of antibiotic. [4]

Antibiotics used in the management of AOM include the following:

  • Amoxicillin

  • Amoxicillin/clavulanate

  • Erythromycin base/sulfisoxazole

  • Trimethoprim-sulfamethoxazole

  • Cefixime

  • Cefuroxime axetil

  • Cefprozil

  • Cefpodoxime

  • Cefdinir

  • Clindamycin

  • Clarithromycin

  • Azithromycin

  • Ceftriaxone

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