What is the association between acute otitis media (AOM) and tympanic membrane perforation (TMP)?

Updated: Dec 14, 2020
  • Author: Robert A Saadi, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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A prospective study by Marchisio et al indicated that an association exists between recurrent episodes of acute otitis media (AOM) and an increased risk for the development of spontaneous tympanic membrane perforation. The study involved 177 children with AOM complicated within 12 hours by spontaneous tympanic membrane perforation. Within that group, recurrent spontaneous tympanic membrane perforation occurred in 92% of those with recurrent AOM and in only 16.9% of those without recurrent AOM. The most common pathogen detected in the middle ear fluid of the study’s children was nontypeable Haemophilus influenzae. [10]

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