Which medical therapies are used in the treatment of sudden hearing loss?

Updated: Aug 28, 2019
  • Author: Neeraj N Mathur, MBBS, MS, DNB(ENT), MNAMS, FAMS; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

No high-quality, randomized, controlled trial exists demonstrating the efficacy of any medical therapy in ISSHL. Hence, no single treatment has been unequivocally shown to be effective, but many strategies have been proposed. Carbogen (5% CO2 +95% oxygen) inhaled for 30 min, 6 times per day (q2h during the day) for 5 days has been used. [30]

A prospective, randomized, noninferiority trial compared the effectiveness of oral prednisone with the effectiveness of intratympanic methylprednisolone in 250 participants with idiopathic sudden sensorineural hearing loss. After 6-month follow-up, the results indicated that based on hearing level 2 months after treatment, the treatments showed similar overall efficacy. [31]


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