Which novel approaches are being considered in the treatment of Merkel cell carcinoma (MCC)?

Updated: Jan 18, 2019
  • Author: Arjun S Joshi, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Answer

Upcoming medical treatment of MCC may involve the Merkel cell polyomavirus. In tumor cells positive for Merkel cell polyomavirus, type I interferon has been shown to increase their apoptotic cell death in vivo through interference of the large T antigen of MCV. [36] Other proteins are the target of experimental vaccines. [37] Further exploration of virus-specific therapy will provide exciting new modes of treatment of this malignant cancer.


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