How is radiation therapy used in the treatment of a Merkel cell carcinoma (MCC) tumor?

Updated: Jan 18, 2019
  • Author: Arjun S Joshi, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Answer

MCC is a radiosensitive tumor. Doses of 45-60 Gy are administered in standard fractions to the surgical site and to the regional lymphatic bed.

A study by Bishop et al indicated that treatment for MCC of the head and neck that includes radiation therapy provides effective local and regional control of the disease. The study, which included 106 patients with the condition who underwent radiation treatment, found that the 5-year actuarial rates for local and regional control of MCC were both 96%. [30, 31]


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