Which factors should be considered in the development of a treatment plan for Merkel cell carcinoma (MCC) tumors?

Updated: Jan 18, 2019
  • Author: Arjun S Joshi, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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MCC is an aggressive malignant tumor with a high propensity for local recurrence, regional nodal involvement, and distant metastases. Treatment depends on the clinical stage at presentation and may involve surgery, radiation therapy, and/or chemotherapy. Multimodal therapy for MCC is often challenging because many patients are elderly and cannot tolerate aggressive treatments. [27] Problems with healing, as well as surgical-site morbidity, must be taken into account to create an effective, individualized therapeutic regimen.

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