Where do Merkel cell carcinoma (MCC) tumors most commonly occur?

Updated: Jan 18, 2019
  • Author: Arjun S Joshi, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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The head and neck is the most common site of occurrence (50%), followed by the lower limbs (30%), the upper limbs (15%), and the trunk (5%). On the face, the eyelids are the most common sites for MCC. The increased incidence in sun-exposed areas suggests that UV light exposure plays a role in the etiology of MCC. However, reports of MCC uncommonly occurring in unexposed sites, such as the genitalia or the oral mucosa, suggest that other factors must play a role.

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