What is the typical growth pattern of Merkel cell carcinoma (MCC)?

Updated: Jan 18, 2019
  • Author: Arjun S Joshi, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Answer

MCC has a propensity to invade the dermal lymphatic system, often resulting in the formation of satellite lesions. About 70-80% of patients with MCC present with localized disease. Approximately 9-25% of patients have local-regional metastases, which manifest as enlarged, firm, painless lymph nodes. Around 1-4% present with widely metastatic disease, which most often involves the skin, lungs, liver, bone, and brain.


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