Which factors increase the risk of hypocalcemia after thyroidectomy?

Updated: Feb 27, 2020
  • Author: Pramod K Sharma, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Risk factors for hypocalcemia after thyroidectomy include Graves disease and malignancy. The type of procedure performed (total thyroidectomy, thyroidectomy with neck dissection, repeat thyroidectomy, subtotal thyroidectomy, near-total thyroidectomy) also affects the risk in transient hypocalcemia after surgery. As more of the parathyroid gland inadvertently removed, the risk of hypocalcemia rises. A retrospective study by Del Rio et al indicated that the rate of early hypocalcemia development following thyroid surgery is higher in female patients than in males (42.0% vs 21.4%, respectively) and in patients who undergo total thyroidectomy rather than monolateral lobectomy (38.8% vs 13.8%, respectively). A perioperative decrease in serum calcium was also correlated with the occurrence of early hypocalcemia. [12]

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