What are the guidelines for the treatment for anaplastic thyroid cancer?

Updated: May 09, 2018
  • Author: Pramod K Sharma, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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No curative treatment currently exists for anaplastic thyroid cancer. The majority of patients present with unresectable or metastatic disease. NCCN guidelines recommend attempting total thyroidectomy in patients with resectable disease. [33]

The 2012 ATA guidelines recommend total lobectomy or total or near-total thyroidectomy with a therapeutic lymph node dissection for patients with intrathyroidal anaplastic thyroid cancer. In patients with extrathyroidal invasion, an en bloc resection should be considered if grossly negative margins (R1 resection) can be achieved. [32]  Both the NCCN and ATA guidelines recommend adjuvant radiation therapy, chemotherapy, or both. [32, 33]

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