What are the NCCN guidelines for assessing malignancy risk in thyroid cancer?

Updated: May 14, 2020
  • Author: Pramod K Sharma, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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The NCCN recommends that FNAB should be the primary test for differentiated thyroid cancer. If FNAB reveals papillary carcinoma, follicular neoplasm, follicular lesion of undetermined significance, or Hürthle cell neoplasm, the following diagnostic recommendations should be undertaken (these are uniform for all differentiated thyroid carcinomas) [33] :

  • Thyroid and neck ultrasonography (including central and lateral compartments) if not previously done
  • Computed tomography (CT) scanning/magnetic resonance imaging (MRI) for fixed, bulky, or substernal lesions (iodinated contrast optimal for cervical imaging)
  • Consider evaluation of vocal cord mobility

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