How is Hürthle cell carcinoma treated in patients with thyroid cancer?

Updated: May 14, 2020
  • Author: Pramod K Sharma, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Hürthle cell carcinomas behave aggressively. Patients with these lesions are at high risk for recurrent and metastatic disease. These tumors most often do not take up radioactive iodine, thereby removing the diagnostic and therapeutic benefits that papillary and follicular carcinomas have. Most surgeons advocate an aggressive approach to treating these tumors. Patients with a diagnosis of Hürthle cell neoplasm based on FNAB findings undergo lobectomy and isthmectomy. If, the final pathologic result confirm Hürthle cell carcinoma, patients return to surgery for completion thyroidectomy. For tumors >5 cm or for palpable lymphatic metastases, total thyroidectomy (including neck dissection for palpable lymph nodes) is often performed during the initial operation.

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