How is anaplastic thyroid carcinoma treated?

Updated: May 14, 2020
  • Author: Pramod K Sharma, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Total or subtotal thyroidectomy is performed for anaplastic thyroid carcinoma when the extent of the tumor permits it. Tracheotomy is needed in cases with airway compromise due to tracheal invasion.

Stage IE lymphomas may be treated with total thyroidectomy followed by postoperative radiation therapy. Surgical excision should not be performed if local infiltration into surrounding tissues is evident. Stage IIE lymphomas are treated with combined chemotherapy and radiation therapy. Doxorubicin or CHOP (ie, cyclophosphamide, hydroxydaunomycin, Oncovin [vincristine], prednisone) is the commonly used chemotherapeutic regimen.

The treatment for thyroid sarcomas is total thyroidectomy. Radiation therapy may be used in an adjunctive setting.

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