What are the sites of extension of allergic fungal sinusitis (AFS)?

Updated: Mar 16, 2018
  • Author: John E McClay, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Although bilateral in 51% of cases reviewed in a large interinstitutional trial of 45 patients, allergic fungal sinusitis (AFS) caused asymmetric involvement of the paranasal sinuses in 78% of patients. Asymmetrical involvement actually is more pronounced in children. In a review of 151 children and adults, the author and colleagues demonstrated that children have more asymmetrical involvement than adults (88% vs 58%) and have a much greater incidence of unilateral disease on presentation than adults (70% vs 37%). Adults in this study presented most often with bilateral disease, but as in the interinstitutional study, asymmetrical disease was seen more often.

Table 3. Sites of Extension of Allergic Fungal Sinusitis From the Paranasal Sinuses*

Table. (Open Table in a new window)

Site

Children (n=10) (25%, 10/40)

Adults (n=23) (23%, 23/100)

Intracranial anterior cranial fossa

3

9

Middle cranial fossa

1

4

Posterior cranial fossa

2

2

Orbit

6

17

Pterygopalatine fossa

1

3

Nasopharynx

3

2

*Multiple sites were affected in some patients.


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