What is the role of total immunoglobulin E (IgE) measurement in the workup of allergic fungal sinusitis (AFS)?

Updated: Apr 13, 2020
  • Author: John E McClay, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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See the list below:

  • Total immunoglobulin E

    • Total IgE values generally are elevated in allergic fungal sinusitis (AFS), often to more than 1000 U/mL (normal values are < 50 U/mL).

    • Total IgE level traditionally has been used to monitor the clinical activity of allergic bronchopulmonary fungal disease.

    • On the basis of similar IgE behavior associated with recurrence of allergic fungal sinusitis (AFS), total IgE levels have been proposed as a useful indicator of allergic fungal sinusitis (AFS) clinical activity.

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