Which medications in the drug class Allergy Extracts are used in the treatment of Allergic Rhinitis in Otolaryngology and Facial Plastic Surgery?

Updated: Jan 02, 2019
  • Author: Quoc A Nguyen, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Answer

Allergy Extracts

Immunotherapy with daily sublingual (SL) tablets may be able to replace weekly injections in some individuals, depending on the offending allergens. SL tablets must be initiated 4 months before the allergen season that is being treated.

Grass pollens allergen extract (Oralair)

SL immunotherapy is indicated for grass pollen–induced allergic rhinitis (with or without conjunctivitis) confirmed by positive skin test or in vitro testing for grass pollen–specific immunoglobulin E antibodies for any of the 5 grass species contained in the product. It consists of 5 purified and calibrated pollen extracts: Perennial Ryegrass (Lolium perenne), Kentucky bluegrass (Poa pratensis), Timothy grass (Phleum pratense), Orchard grass (Dactylis glomerata), and Sweet Vernal grass (Anthoxanthum odoratum).

Timothy grass pollen allergen extract (Grastek)

SL immunotherapy is indicated for allergic rhinitis (with or without conjunctivitis) confirmed by positive skin test or in vitro testing for Timothy grass pollen-specific IgE antibodies.

Ragweed allergen extract (Ragwitek)

SL immunotherapy is indicated for allergic rhinitis (with or without conjunctivitis) confirmed by positive skin test or in vitro testing for ragweed (Ambrosia artemisiifolia) grass pollen-specific IgE antibodies.

House dust mite immunotherapy (Odactra)

The SL tablet consists of standardized extract with consistent biological potency (although the precise mechanisms through which allergen immunotherapy works are unknown). It is indicated for dust mite–induced allergic rhinitis with or without conjunctivitis in people aged 18-65 years, with the allergy confirmed using in vitro testing for IgE antibodies to the house dust mite D farinae or D pteronyssinus or through skin testing using licensed house dust mite allergen extracts.


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