Which medications in the drug class Nonsteroidal anti-inflammatory agents (NSAIDs) are used in the treatment of Nailbed Injuries?

Answer

Nonsteroidal anti-inflammatory agents (NSAIDs)

NSAIDs are commonly used for relief of mild to moderate pain. Effects of NSAIDs in treating pain tend to be patient specific, but ibuprofen is usually the drug of choice (DOC) for initial therapy. Other options include ketoprofen, flurbiprofen, and naproxen.

Ibuprofen (Ibuprin, Advil, Motrin)

Usually DOC for treatment of mild to moderate pain if no contraindications exist. Decreases inflammatory reactions and pain by inhibiting the activity of the enzyme cyclooxygenase, resulting in diminished prostaglandin synthesis.

Flurbiprofen (Ansaid)

Has analgesic, antipyretic, and anti-inflammatory effects. Decreases inflammatory reactions and pain by inhibiting the activity of the enzyme cyclooxygenase, resulting in diminished prostaglandin synthesis.

Ketoprofen (Oruvail, Orudis, Actron)

Used for relief of mild to moderate pain and inflammation. For patients with a small body size, elderly persons, and those with renal or liver disease, initially administer small dosages. Doses >75 mg do not increase therapeutic effects. Administer high doses with caution and closely observe patients' responses.

Naproxen (Anaprox, Naprelan, Naprosyn)

Used for relief of mild to moderate pain. Decreases inflammatory reactions and pain by inhibiting the activity of the enzyme cyclooxygenase, resulting in diminished prostaglandin synthesis.

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Media Gallery

Trephination of a subungual hematoma.
Nailbed repair.

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Author

Darrell Sutijono, MD Attending Physician, Department of Emergency Medicine, Kaiser Permanente Santa Clara Medical Center

Darrell Sutijono, MD is a member of the following medical societies: American College of Emergency Physicians, American Institute of Ultrasound in Medicine

Disclosure: Nothing to disclose.

Coauthor(s)

Mark A Silverberg, MD, MMB, FACEP Assistant Professor, Associate Residency Director, Department of Emergency Medicine, State University of New York Downstate College of Medicine; Consulting Staff, Department of Emergency Medicine, Staten Island University Hospital, Kings County Hospital, University Hospital, State University of New York Downstate Medical Center

Mark A Silverberg, MD, MMB, FACEP is a member of the following medical societies: American College of Emergency Physicians, American Medical Association, Council of Emergency Medicine Residency Directors, Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Chief Editor

Trevor John Mills, MD, MPH Chief of Emergency Medicine, Veterans Affairs Northern California Health Care System; Professor of Emergency Medicine, Department of Emergency Medicine, University of California, Davis, School of Medicine

Trevor John Mills, MD, MPH is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians

Disclosure: Nothing to disclose.

Additional Contributors

Eric M Kardon, MD, FACEP Attending Emergency Physician, Georgia Emergency Medicine Specialists; Physician, Division of Emergency Medicine, Athens Regional Medical Center

Eric M Kardon, MD, FACEP is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association, Medical Association of Georgia

Disclosure: Nothing to disclose.

Acknowledgements

Tom Scaletta, MD President, Smart-ER (https://smart-er.net); Chair, Department of Emergency Medicine, Edward Hospital; Past-President, American Academy of Emergency Medicine

Tom Scaletta, MD is a member of the following medical societies: American Academy of Emergency Medicine

Disclosure: Nothing to disclose.

Which medications in the drug class Nonsteroidal anti-inflammatory agents (NSAIDs) are used in the treatment of Nailbed Injuries?

Nonsteroidal anti-inflammatory agents (NSAIDs)

Ibuprofen (Ibuprin, Advil, Motrin)

Flurbiprofen (Ansaid)

Ketoprofen (Oruvail, Orudis, Actron)

Naproxen (Anaprox, Naprelan, Naprosyn)

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