Which medications in the drug class Vasopressors are used in the treatment of Caffeine Toxicity?

Answer

Vasopressors

These agents are used to increase blood pressure.

Phenylephrine (Neo-Synephrine)

Strong postsynaptic alpha-receptor stimulant with little beta-adrenergic activity. Vasoconstricts arterioles and increases venous return.

Dopamine (Intropin)

Naturally occurring endogenous catecholamine that stimulates dopaminergic, beta1-adrenergic, and alpha1-adrenergic receptors in dose-dependent fashion. At 2-5 mcg/kg/min, acts on dopaminergic receptors in renal and splanchnic vascular beds, causing their vasodilation. At 5-15 mcg/kg/min, acts on beta-adrenergic receptors to increase heart rate and contractility. At 15-20 mcg/kg/min, acts on alpha-adrenergic receptors to increase systemic vascular resistance and raise BP.

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Caffeine content of various foods, beverages, medications, and supplements. Caffeine content is approximate for brewed beverages and chocolate).
Chemical structure of caffeine.

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Author

David Yew, MD Assistant Clinical Professor, Department of Surgery, University of Hawaii, John A Burns School of Medicine; Medical Director and Flight Physician, Hawaii Life Flight, AirMed International

David Yew, MD is a member of the following medical societies: American College of Emergency Physicians, Air Medical Physician Association

Disclosure: Nothing to disclose.

Coauthor(s)

Sophie Kim Boston College

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

John G Benitez, MD, MPH Associate Professor, Department of Medicine, Medical Toxicology, Vanderbilt University Medical Center; Managing Director, Tennessee Poison Center

John G Benitez, MD, MPH is a member of the following medical societies: American Academy of Clinical Toxicology, American Academy of Emergency Medicine, American College of Medical Toxicology, American College of Preventive Medicine, Undersea and Hyperbaric Medical Society, Wilderness Medical Society, American College of Occupational and Environmental Medicine

Disclosure: Nothing to disclose.

Chief Editor

Michael A Miller, MD Clinical Professor of Emergency Medicine, Medical Toxicologist, Department of Emergency Medicine, Texas A&M Health Sciences Center; CHRISTUS Spohn Emergency Medicine Residency Program

Michael A Miller, MD is a member of the following medical societies: American College of Medical Toxicology

Disclosure: Nothing to disclose.

Additional Contributors

James E Keany, MD, FACEP Associate Medical Director, Emergency Services, Mission Hospital Regional Medical Center, Children's Hospital of Orange County at Mission

James E Keany, MD, FACEP is a member of the following medical societies: American College of Emergency Physicians, American College of Sports Medicine, California Medical Association

Disclosure: Nothing to disclose.

China N Byrns Department of Cell and Molecular Biology, University of Hawaii at Manoa

China N Byrns is a member of the following medical societies: Phi Beta Kappa

Disclosure: Nothing to disclose.

Acknowledgements

Jeffrey T Laczek, MD Gastroentology Fellow, Walter Reed Army Medical Center

Disclosure: Nothing to disclose.

Which medications in the drug class Vasopressors are used in the treatment of Caffeine Toxicity?

Vasopressors

Phenylephrine (Neo-Synephrine)

Dopamine (Intropin)

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