What are the less common treatments for caffeine toxicity?

Updated: Oct 24, 2020
  • Author: David Yew, MD; Chief Editor: Michael A Miller, MD  more...
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Additional treatment considerations include the following:

  • Prolonged vomiting should be treated with antiemetic agents.

  • Because caffeine is absorbed rapidly, gastric lavage is unlikely to be useful in patients who present longer than 1 hour after the ingestion.

  • Activated charcoal is effective in limiting gut absorption of methylxanthines and is recommended early in treatment.

  • In rare cases, hemoperfusion or hemodialysis is used in severe caffeine overdose.

  • A case report describes the use of lidocaine, phenylephrine, and hemodialysis to stabilize cardiovascular collapse in a patient with massive caffeine ingestion. [26]

  • A case report describes a patient with multiple episodes of pulseless VT who achieved return of spontaneous circulation after defibrillation, intubation, and amiodarone administration. [27]

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