What is the role of vasopressors in the ED treatment of caffeine toxicity?

Updated: Oct 24, 2020
  • Author: David Yew, MD; Chief Editor: Michael A Miller, MD  more...
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Hypotension can occur in caffeine toxicity. It is related to volume depletion, excessive catecholamine stimulation of beta2-adrenergic receptors, or both. Vasopressors (eg, dopamine, phenylephrine) may be required if hypotension is refractory to intravenous fluid boluses. Phenylephrine is a good choice because it is a pure alpha-agonist, although norepinephrine can be used as well.

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