What is the role of serum caffeine concentration is the diagnosis and treatment of caffeine toxicity?

Updated: Aug 21, 2018
  • Author: David Yew, MD; Chief Editor: Michael A Miller, MD  more...
  • Print
Answer

Serum caffeine concentration determinations do not influence management. Consider the following:

  • Caffeine tests are generally available only at reference or research laboratories and are not clinically useful.

  • Serum theophylline concentrations are more rapidly and widely available than caffeine determinations. Because theophylline is a minor metabolite of caffeine, a positive theophylline assay may be helpful in confirming suspected caffeine toxicity. [24]

  • Patients with severe caffeine toxicity have had serum theophylline concentrations in the therapeutic range (10-20 mg/L).


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!