Which lab tests are performed in the workup of caffeine toxicity?

Updated: Oct 24, 2020
  • Author: David Yew, MD; Chief Editor: Michael A Miller, MD  more...
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In hemodynamically stable patients with mild symptoms and a clear history of caffeine ingestion, no laboratory studies are indicated. Laboratory studies are indicated in patients with moderate-to-severe symptoms of caffeine toxicity. The following studies may be helpful:

  • Complete blood count (CBC)

  • Serum electrolyte, glucose, blood urea nitrogen (BUN), and creatinine concentrations

  • Routine screening for other potentially treatable toxins

  • Total creatine kinase (CK) concentrations

  • Dipstick urinalysis

  • Rapid urine drug screen

  • Serum ethanol concentrations and osmolality (in cases of unknown ingestion or suspected coingestion)

  • Serum pregnancy test

  • Thyroid studies

  • Arterial blood gas analysis

Serum caffeine concentration determinations do not influence management.

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