What are the signs and symptoms of caffeine toxicity?

Updated: Oct 24, 2020
  • Author: David Yew, MD; Chief Editor: Michael A Miller, MD  more...
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When ingested in excessive amounts for extended periods, caffeine produces a specific toxidrome (caffeinism), which consists primarily of the following features:

  • Central nervous system (CNS) – Headache, lightheadedness, anxiety, agitation, tremulousness, perioral and extremity tingling, confusion, psychosis, seizures

  • Cardiovascular – Palpitations or racing heart rate, chest pain

  • Gastrointestinal (GI) – Nausea and vomiting, abdominal pain, diarrhea, bowel incontinence, anorexia

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