Which medications in the drug class Benzodiazepines are used in the treatment of MDMA Toxicity?

Updated: Dec 20, 2017
  • Author: In-Hei Hahn, MD, FACEP, FACMT; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Answer

Benzodiazepines

These agents are important for sedation, muscle relaxation, and seizure management.

Lorazepam (Ativan)

Beneficial for sedative and anticonvulsant effects. Sedation also can lower amphetamine-induced hypertension. DOC for initial treatment of status epilepticus.

Diazepam (Valium, Diazemuls, Diastat)

Depresses all levels of CNS, possibly by increasing activity of GABA; individualize dosage and increase cautiously to avoid adverse effects.


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