How is hyperthermia treated in MDMA toxicity?

Updated: Dec 20, 2017
  • Author: In-Hei Hahn, MD, FACEP, FACMT; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Patients presenting with severe hyperthermia require aggressive cooling measures and adequate fluid resuscitation. Obtain a rectal temperature. Aggressively cool hyperthermic patients, attempting to reduce the core temperature to 101°F within 30-45 minutes.

. Morbidity is directly related to the severity and duration of hyperthermia. Management considerations are as follows:

  • Undress the patient
  • Apply evaporative cooling; spray water onto the body and use an electric fan to circulate the air
  • Apply ice packs to the groin and axilla
  • Iced gastric lavage may be considered
  • In extreme cases, ice-bath immersion may be required for the correction of hyperthermia
  • Control shivering with a benzodiazepine
  • Antipyretics are not useful

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