How are seizures managed in methamphetamine toxicity?

Updated: Oct 29, 2020
  • Author: John R Richards, MD, FAAEM; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Treat methamphetamine-induced seizures like other seizures of unknown etiology, as follows:

  • Administer benzodiazepines IV (see Medication)

  • In patients who do not have IV access, an agent with intramuscular absorption can be used (eg, lorazepam, midazolam)

  • After control of the acute episode, longer-acting agents such as phenobarbital, may be necessary

  • Patients with methamphetamine-induced seizures are at high risk for intracranial hemorrhage and should undergo computed tomography (CT) imaging as soon as possible

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