Which factors determine how long N -acetylcysteine (NAC) therapy is indicated for the treatment late presentations of acetaminophen toxicity/poisoning?

Updated: Jan 17, 2020
  • Author: Susan E Farrell, MD; Chief Editor: Michael A Miller, MD  more...
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Answer

Continuation of NAC therapy is based on the patient's clinical status, on detectable serum acetaminophen, and liver function test results. The Rumack-Matthew nomogram is not valid in cases of late presentation and should not be used to guide medical management in these cases.


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