When is N -acetylcysteine (NAC) indicated in the treatment of delayed presentations of acetaminophen-induced hepatic failure?

Updated: Jan 17, 2020
  • Author: Susan E Farrell, MD; Chief Editor: Michael A Miller, MD  more...
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Because NAC can be beneficial for acetaminophen-induced hepatic failure when patients present more than 24 hours after a single ingestion, medical toxicologists recommend initiating treatment with NAC in patients who present after 24 hours if an acetaminophen concentration is detected and if hepatic injury is evident from liver function studies.

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