When is surgical evaluation indicated in acetaminophen toxicity/poisoning and what are the criteria for liver transplantation?

Updated: Jan 17, 2020
  • Author: Susan E Farrell, MD; Chief Editor: Michael A Miller, MD  more...
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Answer

Surgical evaluation for possible liver transplantation is indicated for patients who have severe hepatotoxicity and potential to progress to hepatic failure. Criteria for liver transplantation include the following:

  • Metabolic acidosis, persistent after fluid resuscitation

  • Renal failure

  • Coagulopathy

  • Encephalopathy

See Treatment and Medication for more detail.


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