Which medications in the drug class Cardiovascular Agents are used in the treatment of Clonidine Toxicity?

Updated: May 30, 2020
  • Author: David Riley, MD, MSc, RDMS, RDCS, RVT, RMSK; Chief Editor: Michael A Miller, MD  more...
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Answer

Cardiovascular Agents

Dopamine (Intropin)

DOC in patients with clonidine toxicity who remain hypotensive after IVF. Stimulates adrenergic and dopaminergic receptors. Hemodynamic effect is dependent on dose. Lower doses predominantly stimulate dopaminergic receptors that, in turn, produce renal and mesenteric vasodilation. Higher doses produce cardiac stimulation and renal vasodilation.

Atropine IV/IM (Atropair)

Vagolytic for patients with bradycardia (eg, SA or AV nodal block).

Doses < 0.5 mg can produce a paradoxical reaction.


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