What is clonidine and what are its clinical uses?

Updated: May 30, 2020
  • Author: David Riley, MD, MSc, RDMS, RDCS, RVT, RMSK; Chief Editor: Michael A Miller, MD  more...
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Clonidine is a central alpha-agonist that is used as an antihypertensive agent. Other reported clinical uses include treatment of opiate and alcohol withdrawal [1] and control of atrial fibrillation with a rapid ventricular rate. It is also used for the following:

  • Pediatric preanesthesia
  • Pediatric postoperative pain
  • Migraine headaches
  • Nicotine addiction
  • Menopausal flushing
  • Attention deficit disorder [2]
  • Tourette syndrome [3]
  • Pediatric panic and anxiety disorders

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