Which medications in the drug class Antidotes, Other are used in the treatment of Vitamin Toxicity?

Updated: Dec 26, 2017
  • Author: Mark Rosenbloom, MD, MBA; Chief Editor: Michael A Miller, MD  more...
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Answer

Antidotes, Other

Activated charcoal is used empirically to minimize systemic absorption of a toxin. It may be of benefit only if administered within 1 hour of ingestion.

Activated charcoal (Actidose-Aqua, EZ-Char, Kerr Insta-Char)

Activated charcoal binds vitamin within the gastrointestinal tract. Multiple doses can be administered to help enhance elimination (although little evidence supports multiple doses of activated charcoal in vitamin overdose). The initial dose may be administered with a cathartic (eg, sorbitol). Subsequent doses should be half of the original dose, without a cathartic, administered as often as every 2-6 hours. Do not administer subsequent doses in the presence of ileus.


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