Which medications in the drug class Corticosteroids are used in the treatment of Vitamin Toxicity?

Updated: Dec 26, 2017
  • Author: Mark Rosenbloom, MD, MBA; Chief Editor: Michael A Miller, MD  more...
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Answer

Corticosteroids

Patients with severe hypercalcemia may require corticosteroids. Corticosteroids have profound and varied metabolic effects.

Hydrocortisone (Cortef, Solu-Cortef)

Glucocorticoids increase urinary calcium excretion. In addition, vitamin D–mediated gastrointestinal calcium absorption is inhibited. However, 1-2 weeks may elapse before serum calcium concentrations decrease. A dosage of 100 mg IV q6h may be administered.


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