Which medications are used in the treatment of vitamin toxicity?

Updated: Jun 01, 2020
  • Author: Mark Rosenbloom, MD, MBA; Chief Editor: Michael A Miller, MD  more...
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Care for vitamin toxicity is generally symptomatic and supportive. Gastrointestinal decontamination may be helpful to minimize amount of vitamin absorbed systemically. Administer charcoal for acute overdoses. Antiemetics or antidiarrheals are helpful if needed.

As previously stated, patients with increased intracranial pressure from vitamin A toxicity may need treatment with medications such as diuretics and mannitol.

In cases of vitamin D toxicity, patients with severe hypercalcemia may require hydration, diuretics, steroids (hydrocortisone 100 mg IV q6h), calcitonin (4-8 IU/kg q6-12h), and/or mithramycin (25 mcg/kg IV over 4-6 h, once daily for 1-4 days).

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