What is the role of imaging studies in the diagnosis for vitamin toxicity?

Updated: Jun 01, 2020
  • Author: Mark Rosenbloom, MD, MBA; Chief Editor: Michael A Miller, MD  more...
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Imaging studies can be employed as follows:

  • Skeletal radiography - For calcifications in chronic vitamin A and vitamin D toxicity

  • Hand radiography - For periosteal calcifications

  • Helical computed tomography (CT) scanning and urography - Obtain a helical CT scan or an intravenous urogram (IVU) for suspected nephrolithiasis (ie, oxalate stones) in patients with vitamin C toxicity

  • CT scanning of the brain - In the presence of neurologic abnormalities, perform a CT scan of the brain, without contrast, only if the prothrombin time (PT) is significantly prolonged and the patient has either a decreased level of consciousness or a focal neurologic deficit

  • Kidneys, ureters, bladder (KUB) film - Indicated for suspected toxicity from iron-containing pills

  • Bone mineral density testing - to evaluate the effect of long-term vitamin A intoxication on reducing bone density and causing osteoporosis [46]

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