Which physical findings are characteristic of vitamin B-6 (ie, pyridoxine) toxicity?

Updated: Jun 01, 2020
  • Author: Mark Rosenbloom, MD, MBA; Chief Editor: Michael A Miller, MD  more...
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Effects of vitamin B-6 (ie, pyridoxine) toxicity include tachypnea and sensory neuropathies, such as the following:

Burning pains

  • Paresthesias

  • Ataxia

  • Clumsiness

  • Paralysis

  • Perioral numbness

Findings range from normal central nervous system (CNS) function to progressive sensory ataxias, profound impairment of position and vibration sense, and diminished tendon reflexes.

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