Which physical findings are characteristic of acute vitamin B-3 (ie, niacin, nicotinic acid) toxicity?

Updated: Jun 01, 2020
  • Author: Mark Rosenbloom, MD, MBA; Chief Editor: Michael A Miller, MD  more...
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Acute toxicity effects related to vitamin B-3 (ie, niacin, nicotinic acid) are prostaglandin-mediated and include the following:

  • Flushing

  • Pruritus

  • Wheezing

  • Vasodilation

  • Headache

  • Increased intracranial blood flow

  • Headache

  • Diarrhea

  • Vomiting

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