What are the signs and symptoms of vitamin C toxicity?

Updated: Jun 01, 2020
  • Author: Mark Rosenbloom, MD, MBA; Chief Editor: Michael A Miller, MD  more...
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The effects of vitamin C toxicity can include the following:

  • Renal colic (ie, nephrolithiasis)
  • Diarrhea
  • Nausea
  • Rebound scurvy - In infants born to women taking high doses
  • Hemolysis - If glucose-6-phosphate dehydrogenase (G6PD) deficiency is present
  • Dental decalcification
  • Increased estrogen levels
  • Occult rectal bleeding

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