What is the role of buprenorphine/naloxone in the treatment of opioid toxicity combined with another narcotic?

Updated: Jul 19, 2021
  • Author: Everett Stephens, MD; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Case reports have surfaced of laypersons using buprenorphine/naloxone intravenously to reverse a heroin overdose. [41] Sublingual use of buprenorphine/naloxone to reverse acute narcotic overdose has also been reported. A combined overdose can potentially provide false reassurance to the practitioner, and caution should be exercised in patients receiving both medications.

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