What are the clinical features of stage 1 iron toxicity?

Updated: Jun 06, 2020
  • Author: Clifford S Spanierman, MD; Chief Editor: Michael A Miller, MD  more...
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Features of stage 1 iron toxicity are as follows:

  • This stage usually occurs within 6 hours after exposure

  • Nausea and diarrhea, often accompanied by abdominal pain, characterize this stage

  • When the intoxication is severe, a hemorrhagic component is observed in conjunction with gastroenteritis

  • The combination of GI fluid loss and blood loss, with additional third-spacing, may result in hypovolemia or shock

  • Fatality occurs in a significant percentage of patients during this stage

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