Which conditions should be included in the differential diagnoses of ethylene glycol (EG) toxicity?

Updated: Dec 05, 2017
  • Author: Daniel C Keyes, MD, MPH; Chief Editor: Sage W Wiener, MD  more...
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Answer

Ethylene glycol should not be confused with diethylene glycol, which essentially consists of two ethylene glycol molecules attached to each other.  Sporadic outbreaks of diethylene glycol toxicity occur in children in the developing world. Patients present with altered mental status, nausea, and vomiting. Laboratory studies show a profound metabolic acidosis and renal failure, similar to ethylene glycol toxicity. Successful treatments with fomepizole and hemodialysis have been reported. [5, 6]


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