What is the incidence of ethylene glycol (EG) toxicity in the US?

Updated: Dec 05, 2017
  • Author: Daniel C Keyes, MD, MPH; Chief Editor: Sage W Wiener, MD  more...
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Ethylene glycol is a relatively common cause of overdose in US emergency departments. In 2018, 5,897 single exposures to ethylene glycol in antifreeze and other automotive products were reported to the American Association of Poison Control Centers (AAPCC). There were 967 minor outcomes, 420 moderate outcomes, 109 major outcomes, and 5 deaths reported. Ethylene glycol exposure was most common in adults, with 4197 single case exposures; there were 469 single case exposures in children younger than 6 years, 125 in those aged 6-12 years, and 436 in those 13-19 years.​ In addition, the AAPCC reported 702 single exposures to ethylene glycol that was not an automotive, aircraft, or boat product, with 91 major outcomes and 14 deaths. [4]

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