Which medications in the drug class Benzodiazepines are used in the treatment of Medication-Induced Dystonic Reactions?

Updated: Feb 19, 2018
  • Author: John Michael Kowalski, DO; Chief Editor: David Vearrier, MD, MPH  more...
  • Print
Answer

Benzodiazepines

Normal balance between dopamine and acetylcholine in the basal ganglia involves modulation from GABA-containing striatonigral neurons. GABA-ergic neurons are inhibitory and antagonize excitatory dopaminergic neurons. GABA agonists (eg, benzodiazepines) may be helpful for acute dystonic reactions when anti-muscarinic agents are not approporiate.

Diazepam (Valium)

Some recommend using diazepam for patients with dystonic reactions refractory to anticholinergic therapy or when such therapy is contraindicated.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!